The Clogher Valley Railway was a 37 mile long narrow gauge railway in County Tyrone and County Fermanagh, Northern Ireland. It opened in May 1887 and closed on 1 January 1942

The railway was mainly situated in rural parts of County Tyrone, which hindered the company's potential profitability. The western terminus was Maguiresbridge, County Fermanagh, where the line shared a station with the Great Northern Railway (Ireland) on the Clones to Enniskillen line. It then proceeded in a north-easterly direction through stations at Brookeborough, Colebrooke, Fivemiletown, Clogher and Augher until reaching Ballygawley station, at which point the line turned in a south-easterly direction to Aughnacloy, Caledon and the terminus at Tynan, County Armagh (where the Great Northern Railway was again met, this time the Clones to Armagh line). Aughnacloy was the line's principal station and the location of the company's headquarters and workshops. Fivemiletown was the second largest station; like a tramway the line passed down the middle of Main Street